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objectieve methoden om

post-exertionele malaise

te "kwantificeren"








In een overzichtsartikel worden meetbare aspecten van post-exertionele "malaise" in kaart gebracht:

  • het effect van fysieke inspanning op de inspanningscapaciteit (na 24 uur);
  • het effect van een fysieke inspanning op de cognitieve prestaties (vr en n een inspanning);
  • het effect van orthostatische stress op het cognitief functioneren (onthouden etc.); en
  • het effect van spieroefeningen (uithoudingsvermogen en het langdurige effect op de kracht).

Uiteraard gaan "vermoeidheidsdeskundigen" deze objectieve maatstaven het liefst uit de weg.





Objective evidence of post-exertional "malaise"

in Myalgic Encephalomyelitis and chronic fatigue syndrome.

J Sports Med Doping Stud. 2015; 5(2): 159. doi: 10.4172/2161-0673.1000159.

Twisk FNM.




Essential elements of Myalgic Encephalomyelitis (ME) are

muscle (weakness) and tenderness, cognitive deficits,

neurological impairments, especially of cognitive, autonomic and sensory functions,

but above all, post-exertional "malaise":

a prolonged increase of symptoms after a minor physical and mental exertion.


Chronic fatigue Syndrome (CFS) is defined as

clinically evaluated, unexplained (persistent or relapsing) chronic fatigue,

accompanied by at least four out of eight specific symptoms,

e.g., sore throat, unrefreshing sleep, and headaches.


Since cognitive deficits and post-exertional "malaise"

are not mandatory for the diagnosis CFS,

only part of the CFS patient group meets the diagnostic criteria for ME.


So, post-exertional "malaise"

is considered to be the distinctive feature of ME.


However, "malaise" is an ambiguous and subjective notion.


In order to assess post-exertional malaise objectively,

several studies have employed widely used methods

to quantify the deviant effects of exertion in ME (CFS) .


This review focuses on

the long-lasting (negative) effects of exercise on the performance indicators of

the physical exercise capacity, the cognitive deficits and the muscle power.





Myalgic Encephalomyelitis, Chronic fatigue syndrome, Exercise, Postexertional malaise, Methods, Assessment