Onlangs berichtte ik over de doorbraak van dr. Light en kollega's (klik hier).
Ook de American Chronicle maakt melding van de toegenomen genexpressie voor de receptoren op zenuwcellen die pijn en vermoeidheid signaleren na een kleine inspanning.
Voor overige berichtgeving in de media, klik op één van onderstaande logo's:
Voor een video van de presentatie die dr. Alan Light over dit onderwerp gaf
op de Utah Offer konferentie in 2007, klik op onderstaand logo:
Overigens betreft de vinding van Light, Light en kollega's niet alleen vermoeidheid,
maar ook om sterke verhoogde pijngevoeligheid en een Th2(/Th17)-shift (klik hier).
Gene Responsible for Chronic Fatigue Syndrome Identified
Lourdes Salvador
October 01, 2009
In recent news, Alan Light, a research professor in the anesthesiology department,
dispels the myth that chronic fatigue syndrome (CFS) is mere laziness.
Chronic fatigue syndrome (CFS) is characterized by
disabling fatigue, unrefreshing sleep, headaches, depression, cognitive dysfunction, and body pain.
More than 4 million Americans suffer from CFS.
While more frequent in women aged 40-59 years, people of all ages, ethnicities, economic statuses, and both sexes may develop CFS.
Light explains that there is a gene that produces a protein which tells the muscles when they are too tired to keep working.
When this gene signals, people feel fatigued and are encouraged to rest.
However, in persons with chronic fatigue syndrome, this gene signals the muscles too early.
This leads to fatigue and exhaustion at much lower levels of activity than most of us experience.
Exercise acts to increase proteins which signal muscles fatigue.
In normal people, these proteins are limited;
however, in people with CFS these proteins increase rapidly and induce a feeling of exhaustion.
Though graded exercise therapy is often recommended for people with CFS,
this finding shows that exercise is extremely counter-productive for people with CFS.
Light's research does not identify what causes this gene to suddenly malfunction in previously healthy people,
though he hopes that CFS will now be viewed as an actual disease.
Even more importantly, a simple genetic test could identify chronic fatigue syndrome for diagnostic purposes.
Other research has linked vaccinations, toxic environmental exposures, and various infections as triggers of CFS.
Toxic exposures may act to alter genetic constitution. Vaccines may act to sensitize the immune system.
There is now sufficient evidence that chronic fatigue syndrome is real and disabling.
Light's research may lead to potential treatments for CFS.
This article originally appeared in
the MCS America News, October 2009 Issue, page 21
http://mcs-america.org/october2009.pdf.
For more articles on this topic, see: MCSA News.
Copyrighted 2009 Lourdes Salvador & MCS America
Met dank aan Dean en andere "korrespondenten".
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